It's hard to see where exactly the tumor and healthy tissue during surgery. But now a new camera capable of promises to improve the success of surgical removal of the tumor.
German researchers have developed a camera that make cancer cells fluoresce in bright colors . According
to them this will help the surgeon to distinguish between cancer with
healthy tissue when removing a tumor in an operation . It can even facilitate the surgeon remove the tumor completely - no longer leave the small cells are difficult to be seen .
" The camera makes residual tumor or metastasis of a millimeter in size that are often overlooked by a surgeon , can be seen in detail , " said Nikolaos Deliolanis from the Fraunhofer Institute for Production Engineering and Automation ( IPA ) in Mannheim .Deliolanis led the research group that developed the camera .See more than the naked eye
This is how it works .Before the surgery , doctors inject dye into the patient's blood . Dyes in question are molecules containing fluorescent antibody designed to attach to tumor cells . These dyes being tested in clinical studies .Molecules emit blue , green , red and other colors as well - depending on the dye .To see color , and whether they have been stuck on the tumor cells , the surgeon while operating the network illuminating light is set at a particular wavelength .Placing the camera above the normal color image that shows the images of any area that shines thanks to a fluorescent dye ." The surgeon receives far more accurate information , " said Deliolanis . " And the patients operated under fluorescent light are most likely to survive . "
" The camera makes residual tumor or metastasis of a millimeter in size that are often overlooked by a surgeon , can be seen in detail , " said Nikolaos Deliolanis from the Fraunhofer Institute for Production Engineering and Automation ( IPA ) in Mannheim .Deliolanis led the research group that developed the camera .See more than the naked eye
This is how it works .Before the surgery , doctors inject dye into the patient's blood . Dyes in question are molecules containing fluorescent antibody designed to attach to tumor cells . These dyes being tested in clinical studies .Molecules emit blue , green , red and other colors as well - depending on the dye .To see color , and whether they have been stuck on the tumor cells , the surgeon while operating the network illuminating light is set at a particular wavelength .Placing the camera above the normal color image that shows the images of any area that shines thanks to a fluorescent dye ." The surgeon receives far more accurate information , " said Deliolanis . " And the patients operated under fluorescent light are most likely to survive . "
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| Left: The camera showed the tumor tissue is marked with a fluorescent dye. Right: Looking tumors without new camera |
The camera can detect up to four dyes at the same time .Inject not only one but several dye into the patient's blood and see how the tumor reacts can also help to find out more about the biochemical structure of a tumor , said researcher Nicholas Dimitriadis , one of the developers .Detecting a brain tumor" Seeing where the tumor ends and the healthy tissue begins is very important when dealing with malignant brain tumors , " said Dimitriadis .When operating on a brain tumor , a surgeon will try to remove as little as possible healthy tissue , Dimitriadis added .However, if the majority of brain tumors are not visible - albeit a small part - can be more aggressive and deadly of the source of the tumor .To assist brain tumor operation , the camera can detect a red dye that has been used in tumor surgery .Doctors inject substances 5 - amino levulinic acid ( 5 - ALA ) into the patient .Compounds encourage patients produce a red dye in the cell body . Because tumors have a high metabolism , they accumulate dye in an amount greater than the other cells and become visible .Ready prototype presentedThe camera has been available for testing in the surgery . The development team will be presenting a prototype at the Medica Trade Fair in Düsseldorf 20-23 November.It is expected that the camera can be immediately integrated into the surgical microscope or endoscope ." We plan to hold the first clinical trial in 2014, " said Dimitriadis . Clinical trials will begin with a focus on brain tumor surgery .
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